your programmer and CAI will most likely only get you 1-2 MPG, your stock tires were probably a 265/75/16 (31.5) so going up to a full 33 inch or a 285/75/16 (32.8) isnt gonna throw your actual mileage off that much, but getting it set to match the actual tire size will help. also going taller means the tire is wider so more contact on the road creating a little more friction creating a little more resistance. Your best thing is keep it under 2000rpm on acceleration from a stop. using the OEM plugs is also a must for vortec motors.