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p0300 2000 chevy 5.3

1165 Views 25 Replies 9 Participants Last post by  popsg
have a 2000 Silverado with a 5.3 and have a p0300. cylinders 1 & 8 are dead misfires at idle but when you get the rpms up the misfire moves and starts jumping around to all cylinders. have new plug wires and plugs have also had the injectors test and cleaned. tested wires from ecm to each injectors wire and they are good. have swap coils from cylinders. 1&8 are still dead till you get high in rpms then it moves to multiple cylinders. did a crankshaft and camshaft sensors and timing gear and chain. and i still have the dead cylinders on 1&8 till i get high in rpms then it moves to other cylinders and did a compression test on the motor have 150psi across all cylinders. pretty stumped any info or recommendations would be extremely helpful tired of throwing parts at it and nothing working.
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I have 48 psi on my 2001 5.3L on my 2nd 150k miles tired fuel pump and still runs fine. It does not bleed off though when turned off.

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